Liverpool will be without star duo Steven Gerrard and Fernando Torres for their crucial Europa League clash with Trabzonspor on Thursday evening.
Midfielder Gerrard is being troubled by a back problem, while injury-prone Spain striker Torres will not be risked, with Sunday's Premier League West Bromwich Albion a priority.
Manager Roy Hodgson told the club's official website:"Steven Gerrard unfortunately has had a recurrence of the back problem which he gets from time to time. Hopefully it won't stop him playing on Sunday.
"With Fernando Torres, we've made the decision that we don't wish to risk him three games in a row at this stage of the season, with him having done so well to get back this quickly."
Daniel Agger (concussion) and Maxi Rodriguez (illness) will also miss out, as the Reds seek to defend a one-goal lead and reach the competition's group stages.
Hodgson added:"Agger played in the game on Monday which was to some extent against medical advice.
"He wanted to play but felt a bit sick after the game. That's mainly due to the concussion he suffered, so it would be foolish for us to risk him on Thursday.
"Maxi is sick. He's in bed at the moment with a bit of gastroenteritis, so he's out of the question."Subscribe to Football FanCast News Headlines by Email